Madurella Mycetomatis Infection Following Allogenic Stem Cell Transplantation for Aplastic Anemia

Dear Editor, Eumycetoma is a slow growing fungal infection, which initially involves the skin and subcutaneous tissues and progresses to involve deeper structures. It is characterized clinically by multiple sinuses draining purulent exudate containing fungal granules. Since the foot is the most common site of initial localization of the lesion, the term “Madura foot” has been used to describe it. Strong clinical suspicion foll categorization of lesion into eumycotic or actinomycotic by suitable culture is essential for diagnosis and effective therapy as delay in diagnosis may be limb or life threatening. We report here, a case of madura foot caused by Madurella mycetomat patient with aplastic anemia following allogenic peripheral blood stem cell transplantation with favourable clinical outcome. A 22-years-old male was diagnosed as a case of very severe aplastic anaemia seven months back when he presented with fever and gum bleeding. He had HLA matched sibling and underwent allogenic peripheral blood stem cell transplantation. Conditioning regimen included fludarabine 30mg/m for 6 days and cyclophosphamide 60mg/m Graft versus host disease (GVHD) prop www.mjhid.org ISSN 2035-3006